The initial application had been rejected in November.
Conditional planning permission has been granted for an extension to the Midlands Regional Hospital Portlaoise.
It'll contain a Respiratory Assessment Unit and an extension to the existing Pediatric Unit.
The HSE was forced to re-apply for permission for the two and three storey project in November, when their initial application was deemed incomplete.
The number of conditions and content of the stipulations attached to the build are as of yet unknown.
Reacting to the news, Laois' Fianna Fail TD, Junior Finance Minister Sean Fleming said:
I will now be in direct contact with HSE senior management to ensure that this project goes to tender as soon as possible. I look forward to this progressing and construction commencing as soon as the tender process is completed.
I want to thank all the management and staff in the hospital in Portlaoise for their work in progressing this project which will result in improved health services for people in Co. Laois and surrounding areas.