Tommy Hewitt's side face Wexford on Saturday evening.
Athlone Ladies side will begin their inaugural national league on Saturday evening.
They kick-off against unbeaten Wexford at 7pm.
The midlanders will face Shelbourne, Peamount and Galway over the next month.
Their manager Tommy Hewitt says his squad are excited to get stuck into a tough opening schedule:
Robbie Henshaw Named To Start For Leinster This Weekend
Offaly Players Shine For NUIG In Fitzgibbon Cup
2019 Win Against Dublin Was My Career Highlight - Willie Dunphy
Westmeath And Offaly Set To Do Battle In O'Byrne Cup
Hearts Sign Offaly Star Ellen Dolan
Offaly Prepped For Galway Walsh Cup Semi
Buccaneers Looking To Start 2026 With A Win
Carlow The Opposition For Laois In Walsh Cup Shield
Midlands Players Feature In Opening Round Of Fitzgibbon Cup
Portlaoise Panthers Aiming For Back To Back Super League Wins
Offaly And Westmeath Victories Set Up O'Byrne Cup Midlands Derby
Maynooth Edge Out Colaiste Choilm In Leinster Quarter Final
Midlands Boxers To Begin National Elite Championships This Week
TUS Midlands Lose First Sigerson Cup Game
Semi-Finals Places Up For Grabs In O'Byrne Cup
TUS Midlands Begin Sigerson Cup Campaign This Evening
Ronan Sweeney Named New Portarlington Manager
I've Always Been A Fan Of The Pre Season Competitions - Mickey Harte
Paul Loonam Set To Fight In February
Athlone Town Secure Signature Of Thomas Considine