It's the third time in a row the two teams have contested the curtain raiser.
Women's Premier Division champions Athlone Town will take on FAI Cup winners Shelbourne in this years Women's President's Cup for the third year runnning.
The match will be the curtain raiser for the start of the new campaign, which starts the following weekend.
The midlanders will be looking for revenge after losing the cup final 6-1 to the Dublin side back in October.
New Athlone boss Colin Fortune says Shelbourne will pose a formidable challenge.
The match kicks off at 3 o'clock at Tolka Park on Saturday.
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