Clara Town and Abbeyleix raise the curtain on this year's campaign.
The Combined Counties Football Leagues return from the summer break this weekend.
The Senior Division title, currently held by Willow Park, will see a number of clubs expecting to compete for top honours.
Along with the title holders, St Peter's of Athlone will be hoping they can secure a league championship after winning a cup double last year.
While Clara Town, Senior Division champions in 2022 and 21, open the season when they take on Abbeyleix Athletic in Father Breen Park on Sunday.
The rest of the league will get their campaign underway on the following weekend.