Wales visit the Aviva on Sunday.
Aaron Connolly and Adam Idah will both be unavailable for Ireland's Nations League games against Wales and Finland this week.
The pair have travelled back to their clubs, having missed last night's Euro 2020 playoff semi final with Slovakia due to being a close contact of a confirmed Covid-19 case.
Meanwhile manager Stephen Kenny says they have reason to be optimistic about the future, despite last night's disappointment.
Their qualification hopes were ended with a penalty shootout defeat to Slovakia in the playoff semi final.
Attention now turns back to the UEFA Nations League campaign - with Wales visiting the Aviva Stadium on Sunday.
And Kenny says the way they took the game to their opposition last night, shows they have the players to do it.