Coolderry, Shinrone, St.Rynaghs and Kilcormac-Killoughey remain in the hunt.
With the last four bracket set, the details have been announced for the fixtures on Saturday week.
Fresh from their triumph over Seir Kieran on the final day of the group phase, Coolderry take on a Shinrone side who secured their passage to this stage with a decisive 20-point victory over Kinnitty.
Shinrone will be looking to advance to a first final since 1960 in the tie against 2018 champions and the faithful's most successful senior club hurling side Coolderry.
They'll lock horns in Birr at 2:30 on November 6th.
St.Rynaghs place atop the group stage was secure ahead of their final day defeat against old rivals Birr.
FULL TIME : @MolloyPrecast Senior Hurling Championship Round 5@BirrCLG 1-23@strynaghs 0-13@BallinamereGAA 2-15@belmont_gaa 1-18@coolderrygaa 0-20@SeirKieran_GAA 1-15@ShinroneGaa 4-19@KinnittyGaa 0-11@KK_GAA 2-24@Drumcullen_GAA 0-10
— Official Offaly GAA (@Offaly_GAA) October 24, 2021
A 13-point defeat will do little to quell their ambitions for a third title in succession in Offaly.
The semi-final will be a repeat of the 2020 final against Kilcormac-Killoughey, which Rynagh's won by six points on the day.
KK pulled no punches in their 20-point demolition of Drumcullen in the final round robin contest and will be hopeful if not quietly confident of another close contest against the 19-times champions.
That one has been fixed for 2:30pm in O'Connor Park on November 6th also.
Fixtures - Offaly Senior Hurling Championship Semi-Finals:
Saturday November 6th
- Coolderry v Shinronr - 2:30pm - Birr
- St. Rynaghs v Kilcormac-Killoughey - 2:30pm - O' Connor Park
Full Interview: Portarlington Footballer Ronan Coffey
Full Interview: The Down's Manager Dermot Power
St Brigid's And St Joseph's Aiming To Reach Leinster Semi-Finals
Ballinagar And Milltown To Meet In Leinster Intermediate Quarter-Final
Ronan Coffey Praises Portarlington’s Young Guns Ahead Of Leinster Quarter-Final
Mauricio Pochettino Set To Be Appointed Manchester United Manager
Darragh Murray Named In Irish Squad For Fiji Clash
Portlaoise Panthers Aiming To Bounce Back In Division One
Portarlington On The Road In Leinster
The Down's Building Towards Leinster Football Quarter-Final
Laois Provisional League Fixtures Revealed
The Harps Manager Praises His Sides Efforts In Leinster
Buccaneers Claim Back To Back AIL Wins
Kilcormac Killoughey Captain Full Of Praise For Goalkeeper
Lough Lene Gaels Suffer Late Heartbreak In Leinster Quarter-Final
Crookedwood Win Leinster Junior Camogie Title
Conor Slevin Wins Dramatic Leinster Quarter-Final For Kilcormac Killoughey
Ireland Secure Comfortable Win Over Argentina
Kilcormac Killoughey Seal Win But Heartbreak For Lough Lene Gaels And The Harps