The competition's deciding game could be this Friday evening.
Ireland boss Andy Farrell has named his team to face France in Friday's Guinness Six Nations opener.
Athlone's Robbie Henshaw will start in the centre, with Garry Ringrose nursing a shoulder injury.
Ronan O'Gara says if all three centres are fit, he has no concerns which two of them start:
Jack Crowley is set to start at out-half, the Munster man is named at 10 ahead of Ciaran Frawley and Harry Byrne.
While Calvin Nash will replace the injured Mack Hansen on the wing.
Ireland Team
15. Hugo Keenan (UCD/Leinster)(36)
14. Calvin Nash (Young Munster/Munster)(1)
13. Robbie Henshaw (Buccaneers/Leinster)(67)
12. Bundee Aki (Galwegians/Connacht)(52)
11. James Lowe (Leinster)(26)
10. Jack Crowley (Cork Constitution/Munster)(9)
9. Jamison Gibson-Park (Leinster)(30)
1. Andrew Porter (UCD/Leinster)(59)
2. Dan Sheehan (Lansdowne/Leinster)(21)
3. Tadhg Furlong (Clontarf/Leinster)(72)
4. Joe McCarthy (Dublin University/Leinster)(5)
5. Tadhg Beirne (Lansdowne/Munster)(46)
6. Peter O’Mahony (Cork Constitution/Munster)(captain)(101)
7. Josh van der Flier (UCD/Leinster)(57)
8. Caelan Doris (St. Mary’s College/Leinster)(36)
Replacements:
16. Ronan Kelleher (Lansdowne/Leinster)(26)
17. Cian Healy (Clontarf/Leinster)(125)
18. Finlay Bealham (Buccaneers/Connacht)(36)
19. James Ryan (UCD/Leinster)(59)
20. Ryan Baird (Dublin University/Leinster)(15)
21. Jack Conan (Old Belvedere/Leinster)(41)
22. Conor Murray (Garryowen/Munster)(112)
23. Ciaran Frawley (UCD/Leinster)(1).
Meanwhile - the France team named by Fabien Galthie shows five changes from the side that started the World Cup defeat to South Africa.
Maxime Lucu will wear the number 9 shirt with Antoine Dupont switching to Sevens ahead of the upcoming Olympic Games.
Yoram Moefana is promoted from the bench to the left-wing.
Francois Cros will start in the back row while there is an all-new second-row of Paul Willemse and newcomer Paul Gabrillagues.
Coach Fabien Galthie has opted for a six forwards/ two backs bench split.
Kick off at the Stade Velodrome is set for 8pm Irish time.
Our 6 Nations coverage is with thanks to The Bed Shed Kilbeggan, who offer an express delivery and assembly service right across the Midlands for the full range of over 40 beds and mattresses on offer in their showroom. . .find The Bed Shed on Facebook and Instagram for their latest offers
Westmeath Ladies Face Crucial Contest In Athlone
Laois Face Westmeath In Camogie League Derby
"They Do The Upmost For Their County" - Offaly Playing For Promotion Play-Offs
Buccaneers Hoping For Bounce Back Win Against UL Bohs
Athlone Insist Focus Is On DLR Waves After Sullivan Resignation
Westmeath Manager Expects Two Point Onslaught In Wexford
Patchy Laois Wrap League Campaign Against Table Topping Down
Laois And Offaly Begin Minor Hurling Campaign
"Special Doesn't Do These Lads Justice"
Upwardly Mobile Athlone Take On Treaty
Ireland Name Nine New Caps For Six Nations Squad
Panthers Promotion Hopes Dashed On Final Weekend
Colaiste Mhuire Mullingar: All Ireland Champions
Dublin Sink Offaly In Camogie
Lowry Looks On Shaky Ground Since Cognizant Collapse
"Unhappy" Laois Leave Fermanagh With Some Regret
Laois Ladies Football Legend Honoured By County Council
Westmeath School Primed For All Ireland Final Shot
Offaly Relegated After Cavan Defeat
Offaly And Longford Chase Semi-Final Spot In Division Four