The former Antrim boss recently received the news after breaking his arm in an accident.
Darren Gleeson is leaving his role as the manager of the Laois senior hurlers with immediate effect following a cancer diagnosis.
The Tipperary man made the announcement over the weekend - saying the medical advice he's received means it's "essential" he takes the appropriate time to focus on his treatment and recovery.
The former Antrim boss was announced as the new O'Moore County manager as recently as the end of August.
Gleeson says he had "extensive plans" in place and was looking forward to what the future held.
He's also underlining his appreciation for the support of the Laois county board.
Laois GAA meanwhile are thanking Gleeson for the "huge amount of work and enthusiasm" he brought to the role.
The appointment was broadly welcomed when announced.
The two-time All Ireland winning Tipp keeper had already proven an effective manager at inter-county level following his time in Antrim.
Gleeson won two Joe McDonagh Cups and kept the Saffrons in division one hurling for three seasons in his time over the county.
Statement from Darren Gleeson & Laois GAA pic.twitter.com/1KZjRpGq5N
— Laois GAA (@CLGLaois) November 16, 2024
Full Interview: Portarlington Footballer Ronan Coffey
Full Interview: The Down's Manager Dermot Power
St Brigid's And St Joseph's Aiming To Reach Leinster Semi-Finals
Ballinagar And Milltown To Meet In Leinster Intermediate Quarter-Final
Ronan Coffey Praises Portarlington’s Young Guns Ahead Of Leinster Quarter-Final
Mauricio Pochettino Set To Be Appointed Manchester United Manager
Darragh Murray Named In Irish Squad For Fiji Clash
Portlaoise Panthers Aiming To Bounce Back In Division One
Portarlington On The Road In Leinster
The Down's Building Towards Leinster Football Quarter-Final
Laois Provisional League Fixtures Revealed
The Harps Manager Praises His Sides Efforts In Leinster
Buccaneers Claim Back To Back AIL Wins
Kilcormac Killoughey Captain Full Of Praise For Goalkeeper
Lough Lene Gaels Suffer Late Heartbreak In Leinster Quarter-Final
Crookedwood Win Leinster Junior Camogie Title
Conor Slevin Wins Dramatic Leinster Quarter-Final For Kilcormac Killoughey
Ireland Secure Comfortable Win Over Argentina
Kilcormac Killoughey Seal Win But Heartbreak For Lough Lene Gaels And The Harps