Leo Cullen has made widespread changes to his starting team after a narrow victory over Munster.
Leinster head coach Leo Cullen had made 14 changes to his side for Monday's interprovincial derby against Ulster in the URC.
Athlone's Robbie Henshaw returns to a starting position, lining up at inside centre for his 82nd cap for the Blues.
Rob Russell is the only player retained in the starting line-up following the St Stephen's Day win over Munster at Thomond Park.
Jamison Gibson Park has been passed fit to play at scrum-half and will be partnered at out-half by Sam Prendergast.
Ulster welcome back Steven Kitshoff and Rob Herring to their line-up for the game at the RDS.
NHL: Offaly Face Limerick In Final League Game
Portlaoise Panthers Looking To Continue Good Form In Division One
Shane Lowry In Action In Florida This Week
NHL: Improving Each Week The Goal For Laois
Grainne Walsh Progresses At Strandja Memorial Tournament
Crunch Weekend For Midlands Sides In National Camogie League
James Gormley Named On Irish Squad For FIBA EuroBasket Qualifiers
Portlaoise Panthers Suffer Tough Defeat In Super League
CCFL: St Peter's Extend Their Advantage At Top Of Premier Division
NFL: Relegation Firmly On The Cards For Offaly
Laois "Devastated" By Defeat Despite Delivering "Manliness" - Justin McNulty
Westmeath Ladies Bag First Win Of League Season
Big Camogie Wins for Westmeath and Laois Over The Weekend
Fitzgerald "Relieved" After Squeaking Past Kerry
NHL: Galway Prove Too Strong For Offaly
Former Laois And Offaly GAA Manager Honoured By An Garda Síochána
Athlone Town Make It Two Wins From Two In First Division
Lee Fitzpatrick Scores Try For Ireland U20s In England
NFL: Westmeath Move Closer To Promotion
Shane Lowry Finishes Strong In California