The Leinster centre has failed to recover for the middle game of this year's campaign.
Andy Farrell has refreshed his Ireland squad ahead of Saturday’s Six Nations test away to Italy.
Joey Carbery returns to the fold, having been omitted from the squads that beat Wales and France.
With Tadhg Beirne and Joe McCarthy out injured, Scott Penny and Kieran Treadwell have received call-ups.
Dan Sheehan and Cian Healy have been passed fit following hamstring injuries.
But Tadhg Furlong, Robbie Henshaw and Jamison Gibson-Park all remain absent.
Tullamore Town FC Ready For Red Letter Weekend
Busy Bank Holiday Weekend In Store For Athlone Town
Big Weekend Ahead In Leinster Minor And U20 Hurling Championships
Leinster SFC: Opportunity Beckons For Westmeath
Westmeath Footballer Luke Loughlin Ruled Out For Remainder Of Season
Laois And Westmeath Battle For Place In Leinster LGFA Decider
Alex Dunne Set For Action In Miami This Weekend
Fundraising Walk Planned For Westmeath Man Left Paralysed In Freak Accident
Shane Lowry In Action In Miami This Week
Westmeath Secure Leinster Minor Football Quarter Final
CCFL: Two Draws In Senior Division
Potential Hometown Fight On The Cards For Joe Ward
Ava O'Connor Breaks Personal Steeplechase Record
Laois Fixture In Two Weeks A "Massive Game" - Kevin O'Brien
Camross Camogie Honoured In Laois Following Historic All-Ireland Triumph
Athlone Town Secure Vital Win In Women's Premier Division
Laois And Westmeath To Clash In Leinster Camogie Decider
Leinster SHC: Offaly Suffer First Defeat Away To Galway
Draw Made For First Round Of Tailteann Cup
Offaly Soccer Club Opens Doors To All With Football For All Initiative