Laois also have a crucial contest with Antrim, and Offaly make the trip to Wexford.
Joe Fortune is expected to welcome back a couple of key players as Westmeath look to cement their place at the top of Division 2A of the Allianz Hurling League.
Davy Glennon is chief among those who will be expected to slot staright back into the starting XV once available.
The Lake County welcome Down to TEG Cusack Park in Mullingar on Sunday and Fortune had this update on his injury list:
Elsewhere this weekend, Offaly make the trip to Wexford as they continue to fight relegation back to the second tier.
While Laois face a crucial contest with Antrim, knowing it's likely the loser will be confined to a relegation playoff against the Faithful in a matter of weeks.
All Ireland Glory Achieved By Camross
Dublin Lions End Portlaoise Panthers' Perfect Home Record
Success For Camross But Heartbreak For Tubberclair
Portlaoise Panthers Back In Super League Action This Weekend
Midlands Stars Set For European Cross Country Championships
Laois U20 Hurler And Footballer Of The Year Revealed
Camross Has Nothing To Lose This Weekend - Arien Delaney
Robbie Henshaw Named To Start For Leinster's Champions Cup Clash
Leinster Glory The Target For Tubberclair This Weekend
Portlaoise Panthers Aiming To End Losing Streak
Camross Getting Set For All Ireland Final
Westmeath Boxers Set To Compete At U17 European Championships
Portlaoise Panthers U20s Seal Semi-Final Place In National Cup
Midlands Beko Club Champions Recognised At Croke Park
CCFL: Four Teams Progress In Combined Counties Shield
Offaly Olympian Reveals Arsenal Dream
Buccaneers Claim First Home Win In Over Two Years
Pat Roe Steps Down As Portarlington Manager
St Michael's And Wheery To Meet In Offaly U20 Football Final