Seir Kieran are looking for a first championship win.
St Rynagh's may still be carrying the scars of a heavy defeat at the hands of the county champions ahead of their last group stage outing in the Offaly Senior Hurling Championship.
The Banagher club were expected in some quarters to challenge Kilcormac Killoughey for top honours this season before the two clubs met earlier this month.
KK however ran out 23 point winners in a blow out in Rath.
Rynagh's bounced back to register a comfortable win against Tullamore, and face a winless Seir Kieran in Birr on Friday evening.
Clareen have two games in which to move themselves away from the foot of the Group One table.
Midlands 103 commentator Joe Troy says Rynagh's need momentum:
Throw in at Grant Heating St Brendan's Park is set for 6.30pm on Friday evening.
Our coverage of Offaly GAA is with thanks to Leahy Midland Auctioneers.
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