The Laois club open their campaign against Ulster University in Jordanstown.
Portlaoise Panthers first game back in the top tier of Irish basketball brings them up the M1 to Ulster University.
Niall Berry returns as head coach for the Laois team who have retained both Alyssa Velles and Jessica Fressle from their MissQuote.ie Division One promotion campaign.
Ulster University caught the injury bug early a year ago and they look primed to improve on their 9th place finish in 2023.
The Jordanstown outfit have made no fewer than seven additions to their roster, including Irish international Abigail Rafferty who returns from DeSales University in the USA.