He signed for a 2 over par round on day two.
It's been a disappointing two days back on Irish soil for the Open Champion.
A five over par round of 75 yesterday has been followed by a 72 today to leave him on 7 over par and he won't be playing the weekend at Galgorm Castle.
It was always a big ask a week after a gruelling US Open course, given the trans-Atlantic travel, time difference and adjusting to a different set of conditions.
Lowry will however be disappointed that, after battling well in difficult conditions at Winged Foot seven days ago that he couldn't take advantage of an easier set up the last two days.
He's not the only Irishman below the cut mark, Padraig Harrington and Paul Dunne have finished on +6 and +9 respectively.
A delay to play this morning means not everyone was able to complete their second round today but it would take a big shift for the cut mark to move any further than it's current +5 mark.
Portlaoise Panthers Back In Super League Action This Weekend
Camross Name Tomas Burke As New Hurling Manager
Midlands Stars Set For European Cross Country Championships
Laois U20 Hurler And Footballer Of The Year Revealed
Camross Has Nothing To Lose This Weekend - Arien Delaney
Robbie Henshaw Named To Start For Leinster's Champions Cup Clash
Leinster Glory The Target For Tubberclair This Weekend
Portlaoise Panthers Aiming To End Losing Streak
Camross Getting Set For All Ireland Final
Westmeath Boxers Set To Compete At U17 European Championships
Portlaoise Panthers U20s Seal Semi-Final Place In National Cup
Midlands Beko Club Champions Recognised At Croke Park
CCFL: Four Teams Progress In Combined Counties Shield
Offaly Olympian Reveals Arsenal Dream
Buccaneers Claim First Home Win In Over Two Years
Pat Roe Steps Down As Portarlington Manager
St Michael's And Wheery To Meet In Offaly U20 Football Final
Athlone Town Confirm Two New Signings Ahead Of 2026 Season
Kelly Brady Named Personality of the Year
Former Irish Soccer Legend Backs Offaly Community After Arson Attack