He signed for a 2 over par round on day two.
It's been a disappointing two days back on Irish soil for the Open Champion.
A five over par round of 75 yesterday has been followed by a 72 today to leave him on 7 over par and he won't be playing the weekend at Galgorm Castle.
It was always a big ask a week after a gruelling US Open course, given the trans-Atlantic travel, time difference and adjusting to a different set of conditions.
Lowry will however be disappointed that, after battling well in difficult conditions at Winged Foot seven days ago that he couldn't take advantage of an easier set up the last two days.
He's not the only Irishman below the cut mark, Padraig Harrington and Paul Dunne have finished on +6 and +9 respectively.
A delay to play this morning means not everyone was able to complete their second round today but it would take a big shift for the cut mark to move any further than it's current +5 mark.