Conor Murray is also among the replacements.
Three Irish players have been named in the British and Irish Lions team for tomorrow's game against the Sharks.
Tadhg Furlong, Tadhg Beirne and Jack Conan have all been handed starting roles by Warren Gatland.
Jamie George captains the team, with Conor Murray among the replacements.
The line-up shows a total of 13 changes from the side that played the same opposition earlier this week.
Lions Squad:
5. Liam Williams (Scarlets, Wales)
14. Anthony Watson (Bath Rugby, England)
13. Elliot Daly (Saracens, England)
12. Chris Harris (Gloucester Rugby, Scotland)
11. Duhan van der Merwe (Worcester, Scotland)
10. Dan Biggar (Northampton, Wales)
9. Gareth Davies (Scarlets, Wales)
1. Rory Sutherland (Worcester, Scotland)
2. Jamie George (Saracens, England) (captain)
3. Tadhg Furlong (Leinster, Ireland)
4. Maro Itoje (Saracens, England)
5. Jonny Hill (Exeter, England)
6. Tadhg Beirne (Munster, Ireland)
7. Hamish Watson (Edinburgh, Scotland)
8. Jack Conan (Leinster, Ireland)
Substitutes:
16. Ken Owens (Scarlets, Wales)
17. Wyn Jones (Scarlets, Wales)
18. Kyle Sinckler (Bristol, England)
19. Courtney Lawes (Northampton, England)
20. Sam Simmonds (Exeter, England)
21. Tom Curry (Sale, England)
22. Conor Murray (Munster, Ireland)
23. Finn Russell (Racing 92, Scotland)
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