The Women's Premier Division side had too much firepower for Glentoran in Blanchflower Stadium.
Athlone Town came from behind away from home to win a seven goal contest in the opening game of their Women's All Island Cup campaign.
The midlanders found themselves 2-1 down before going on to beat Glentoran 5-2.
Casey Howe opened the scoring for Ciaran Kilduff's side before goals by Kerry Beattie and Nadene Caldwell meant the hosts were ahead at the break.
Kerryanne Browne levelled before Howe's second put Athlone back in front.
Ciara O'Neill extended their lead before Jesi Rossman put the seal on their victory.
A number of Town's finishes were out of the top drawer:
Athlone return to action this weekend when they face Shelbourne in the Women's Premier Division.
Full Interview: Portarlington Footballer Ronan Coffey
Full Interview: The Down's Manager Dermot Power
St Brigid's And St Joseph's Aiming To Reach Leinster Semi-Finals
Ballinagar And Milltown To Meet In Leinster Intermediate Quarter-Final
Ronan Coffey Praises Portarlington’s Young Guns Ahead Of Leinster Quarter-Final
Mauricio Pochettino Set To Be Appointed Manchester United Manager
Darragh Murray Named In Irish Squad For Fiji Clash
Portlaoise Panthers Aiming To Bounce Back In Division One
Portarlington On The Road In Leinster
The Down's Building Towards Leinster Football Quarter-Final
Laois Provisional League Fixtures Revealed
The Harps Manager Praises His Sides Efforts In Leinster
Buccaneers Claim Back To Back AIL Wins
Kilcormac Killoughey Captain Full Of Praise For Goalkeeper
Lough Lene Gaels Suffer Late Heartbreak In Leinster Quarter-Final
Crookedwood Win Leinster Junior Camogie Title
Conor Slevin Wins Dramatic Leinster Quarter-Final For Kilcormac Killoughey
Ireland Secure Comfortable Win Over Argentina
Kilcormac Killoughey Seal Win But Heartbreak For Lough Lene Gaels And The Harps