Clogher Valley were 19 points the better against Tullamore earlier this season.
Tullamore will have one more opportunity to push for a promotion play-off place after they lost to Omagh Academicals on Saturday.
The final score was 37 - 21.
They trail Bruff, who occupy the final play-off position, by six points with a maximum of ten left on the table in the regular season.
The Offaly club return to action this weekend against table toppers Clogher Valley.
Fail to win there and Tullamore will be playing in Division 2C again next season.
Kick off in Spollanstown is set for 2.30pm on Saturday.
James Gormley Named On Irish Squad For FIBA EuroBasket Qualifiers
Portlaoise Panthers Suffer Tough Defeat In Super League
CCFL: St Peter's Extend Their Advantage At Top Of Premier Division
NFL: Relegation Firmly On The Cards For Offaly
Laois "Devastated" By Defeat Despite Delivering "Manliness" - Justin McNulty
Westmeath Ladies Bag First Win Of League Season
Big Camogie Wins for Westmeath and Laois Over The Weekend
Fitzgerald "Relieved" After Squeaking Past Kerry
NHL: Galway Prove Too Strong For Offaly
Former Laois And Offaly GAA Manager Honoured By An Garda Síochána
Athlone Town Make It Two Wins From Two In First Division
Lee Fitzpatrick Scores Try For Ireland U20s In England
NFL: Westmeath Move Closer To Promotion
Shane Lowry Finishes Strong In California
Westmeath Drifter Sets Sights On Success In 2026
Offaly’s Alex Dunne Joins Alpine’s Young Driver Programme
NHL: Laois And Kerry Clash In Division Two
Shane Lowry Cards Opening Round 73 At Genesis Invitational
Athlone Town Aiming For Back To Back League Wins