Melissa was last seen on Wednesday.
Gardaí are seeking assistance in locating missing teenager in the midlands.
16-year-old Melissa McDonnell was last seen in the Pearse Street area of Mullingar, County Westmeath, at approximately 6pm on Wednesday 18th October.
Melissa is described as being approximately 5 foot 2 inches in height with a thin build, blonde hair and blue eyes.
When last seen, Melissa was wearing a grey jumper, a green sleeveless jacket and black runners.
Gardaí are concerned for Melissa's welfare.
Anyone with any information on Melissa's whereabouts are asked to contact Mullingar Garda station on 044 938 4000, the Garda Confidential Line on 1800 666 111, or any Garda station.
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