Met Eireann have issued the alert to come into effect from 11 pm tonight.
A status yellow low temperature and ice warning has been issued for 10 counties.
Laois, Offaly, Westmeath, Carlow, Kildare, Kilkenny, Wicklow and Tipperary will come under the advisory from 11pm until 8 tomorrow morning.
People are being advised that there could be animal welfare issues if they're kept outdoors and motorists may face difficult travelling conditions.
A status yellow snow and ice warning has expired for the North West but remains in place in the North until midday.
Midlands Gardaí Appeal For Witnesses To Fatal Crash
Midlands Security & Defence Analyst Says Hoax Bomb Threats Aimed To Intimidate
Almost €446,000 Allocated To Midlands Community Centres And Clubhouses
Midlands Family Takes On Ireland’s Fittest Family Challenge
5K Fundraiser To Support Motor Neurone Disease Association Takes Place In Westmeath
No Slowing Down With Age As Westmeath Bowlers Shine At 14th Annual National Bowls Competition
Woman Appears In Court Over €280k Cannabis Seizure In Midlands