Cocaine, cannabis, and cash were found in Westmeath and Kildare on Saturday.
Two men are due in court this afternoon in connection with the seizure of €2.1m drugs, which was discovered following searches in Kildare and Westmeath at the weekend.
They are due to appear before Athlone District.
Cocaine and cannabis and over €110,000 in cash was found following searches in both counties on Saturday.
Five men and one woman were arrested - two of the men appeared before Naas District Court this morning.
Another man and woman have since been released without charge pending a file to the Director of Public Prosecutions.
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