Bundee Aki replaces Robbie Henshaw in the centre.
Head coach Andy Farrell's made four changes to his starting fifteen for Saturday's Autumn Nations Cup match against England.
Two of the changes are enforced with outhalf Johnny Sexton and Robbie Henshaw ruled out of the Twickenham clash through injury.
Ross Byrne and Bundee Aki come in to replace them.
Keith Earls starts on the wing in place of Andrew Conway who is left out of the matchday squad but Jacob Stockdale is named in the replacements.
CJ Stander replaces Josh van der Flier in the only change to the pack.
Team in Full:
15. Keenan, 14. Earls, 13. Farrell, 12. Aki, 11. Lowe, 10. R. Byrne, 9. Gibson Park;
1. Healy, 2. Kelleher, 3. Porter, 4. Roux, 5. Ryan (C), 6. Stander, 7. O'Mahony, 8. Doris.
#TeamOfUs
— Irish Rugby (@IrishRugby) November 18, 2020
4⃣ Changes and a new captain, here's the details on the Ireland team. #ENGvIRE #ShoulderToShoulder #AutumnNationsCup ⤵️https://t.co/tXfcTcXDQE
Laois And Offaly Clubs Sign Off In Leinster After Championship Defeats
Midlands Athletes Shine In Derry For National Cross Country
Willie Hyland Calls Time As Clough Ballacolla Depart Leinster Championship
€201k - Athlone Town Enjoy Massive European Windfall
Westmeath's Kieran Martin Announces Retirement
"Work Rate, Determination, And Drive" - Lusmagh's Ruairi Kelly Looks Forward To Leinster Semi-Final
Portlaoise Panthers Back In Action This Weekend
Henshaw Misses Out As Prendergast Claims 10 Jersey For Boks Contest
Ireland Get Czechia For World Cup Play-Off
Laois Champions Ready To Take On "The Greatest" On Sunday
Republic Of Ireland In Pot Three For World Cup Qualifiers
Casey O'Gorman Competes At Valencia Moto3
Darragh Clinton Retires From Inter County Hurling
CCFL: Temple Villa And Mountmellick United Draw In Premier Division
Clara And Tubberclair Progress In Leinster Intermediate Championship
Former Offaly GAA Chair Headlines 'Breakfast And Banter' Event
Tullamore Brought A Real Intensity To The Down's - Dermot Power
Buccaneers Denied Second AIL Win Away To Skerries
Tullamore Survive Late Fightback From The Down's
Mixed Weekend For Portlaoise Panthers