Westmeath still has the highest number of people on the register.
The number of people signing on in the midlands has decreased by just over 700.
Westmeath remains the county in the region with the highest number, at 4,101.
Laois saw 3,254 people on the live register in September and the number in Offaly reached 3,057.
Nationally however, there was an increase of 4,200, bringing the total on the live register to 180,200.
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