The HSE is encouraging anyone who feels unwell after taking drugs to seek medical help.
Gardaí are not monitoring drug surrender bins at Electric Picnic, according to the HSE.
The Health Service Executive is running a pilot drug surrender programme at the festival in Stradbally, Co Laois, as it returns after a two-year absence.
The HSE is urging anyone who feels unwell after taking a substance to hand it over to be tested.
The drugs will be tested immediately, and if a particularly dangerous strain is identified, a message will be announced at the festival.
Eamonn Keenan, HSE national lead for addiction services, fears people will hesitate to come forward:
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