Crews have assisted more than 1,000 people since the Athlone base was set up in 2012.
Lough Ree RNLI is hoping to raise €100,000 to finish to their new boat house in Westmeath.
€1.2 million is being spent on the building in Coosan Point, which will provide a base for the 35 volunteers and their lifeboat 'Tara Scougall'.
Crews have responded to 400 call-outs and assisted more than 1,000 people since it was founded in 2012.
PRO Tom McGuire says the project is expected to be finished by the end of the summer: