Three U-20's are among eleven who come into the set up.
Eleven new faces will be part of Michael Fennelly's hurling panel for 2021.
St Rynagh's Luke O'Connor, Padraig Cantwell of Shamrocks and Shinrone's Eamon Cleary are being promoted from the U-20's.
John Murphy and Aaron Maher of Ballinamere, Jordan Quinn of Kilcormac/Killoughey, Lusmagh's Evan Kelly, Drumcullen's Podge Guinan, Conor Clancy of St Rynagh's and Birr duo Rory Carty and Dylan Watkins also come into the set up.
Our Offaly GAA commentator Joe Troy says they'll have to adapt quickly: