A light aircraft was also seized in Longford.
120 kilogrammes of cocaine, with an estimated street value of €8.4 million, has been recovered in Westmeath.
Two vehicles were intercepted by gardaí at 6 o'clock yesterday evening at two locations in the Lough Owel area.
Several communication devices were also found, and a series of follow up searches led to a light aircraft being seized in Longford.
Two males, age 54 and 40 years, have been arrested on suspicion of drug trafficking and are currently being detained.
Former Assistant Garda Commissioner, Pat Leahy, says it's a good day for Gardai and communities around the country:
The seizure occurred as a result of ongoing investigations targeting drug related organised crime activity by personnel attached to the Garda National Drugs & Organised Crime Bureau supported by other national units.
Man Hospitalised With Serious Injuries Following Offaly Crash
Biodiversity Children's Book Launches In Midlands
Over €3.8m In IT And Minor Works Grants Going To Midlands Schools
Midlands Property Prices Continuing To Rise
Mercosur Vote Down To The Wire - Midlands MEP
Offaly Community Sports Facility To Remain Closed Over Christmas
Westmeath Security Expert Welcomes Gardai Training For EU Presidency
Lower Childcare Fee Caps Could Lead To Closures - FECP
Gardai Investigating Potentially Suspicious Approach Of Child In Laois
Midlands Animal Rescue Shelter Unequivocally Against Fox Hunting
Judge Disappointed And Surprised By AG Ruling On Burke Contempt Of Court Referral
Five Maternity Reviews At Portiuncula Hospital Ongoing
Gardaí Confirm Discovery Of Man's Body At Midlands Premises
Laois Senator Warns Blister Pack Funding Cut Will Lead To Dangerous Confusion
Call To Fast-Track Living City Initiative For Westmeath Town
Midlands Community Sports Facility Closing With Immediate Effect
Man Arrested In Connection With Fatal Offaly Fire Released Without Charge
Westmeath Waste Facility Remains Temporarily Closed
Laois Man To Be Laid To Rest Friday
Laois Community Safety Partnership To Start January