The stretch of road between Athlone and Mullingar is currently closed.
Emergency services are at the scene of a serious collision in Westmeath.
A stretch of road between Loughnavalley and Ballinea is closed and diversions are now in place.
The incident occurred earlier this morning on the R390 which connects Mullingar and Athlone.
Gardaí are advising morotists to expect a 90 minute delay in the area.