Robbie Henshaw starts at inside centre.
Ireland host Wales in their opening game of the inaugural Autumn Nations Cup this evening.
James Lowe wins his first cap for Ireland on the wing, while Ulster fly-half Billy Burns is in line to make his debut from the bench.
Wales go into the game at the Aviva Stadium on the back of five successive defeats - Ireland flanker Peter O'Mahony says both sides are determined to win:
#TeamOfUs
— Irish Rugby (@IrishRugby) November 12, 2020
👋 @JamesLowe_03 👀#ShoulderToShoulder #GuinnessSeries #AutumnNationsCup #IREvWAL pic.twitter.com/Y5J7Vph1Y9
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