There are four games taking place over the course of Saturday and Sunday.
The Laois Senior Hurling Championship returns this weekend after a two week break.
This weekend's round of fixtures could be decisive in the later stages of this year's campaign.
The action gets underway on Saturday from Group A as reigning champions Clough/Ballacolla and The Harps will want to get back on track after their opening round defeats.
They face off in O'Moore Park with hopes of getting a first win on the board, throw in is at 5:30pm.
Afterwards at 7:00pm, Rathdowney Erill and Rosenallis will be hoping to build on their first round wins as they go head-to-head also in O'Moore Park.
On Sunday it's the turn of Group 2 as Castletown take on Borris in Ossory with a 1:30pm throw in time. Similarly to Group A, both sides began with defeats in round 1, with the hopes of trying to gain some momentum ahead of the final round of fixtures.
And rounding off the action on Sunday afternoon will be last season's beaten finalists Camross against Abbeyleix St Lazarians.
A win for either side could be enough to see them through to the knockout stages in attempts to claim the Bob O'Keefe Cup.
There Are Very Strict Rules When It Comes To International Sport - Tanaiste
Westmeath SFC: Great To Win At The Weekend - John Heslin
2027 Irish Open To Take Place Next July
Offaly’s First All-Ireland Winning Hurling Manager Andy Gallagher Dies Aged 89
Laois SFC: Killeshin Deliver Knockout Blow To Portlaoise
Westmeath SFC: Moate All Whites Turn Attention To County "Standard Bearers"
Town Continue Rich Vein Of Form With Creditable Students Draw
Offaly SFC: Shamrocks And Tullamore Secure Semi-Final Spots
John Heslin Aiming To Feature For Westmeath Next Season
Westmeath SFC: St Loman's Mullingar And Moate All Whites Progress
Athlone Town Move Closer To Women's Premier Division Title
Alex Dunne Keeps F2 Title Hopes Alive With Spanish GP Podium
Trump To Lift US Tariff On Irish Whiskey After Talks With Shane Lowry
Lowry Breaks Title Drought With Magnificent Irish Open Victory
Shane Lowry Leading The Way At The Irish Open
Alex Dunne Secures Front Row Start For F2 Feature Race In Madrid
Former Golf Coach Stunned With Stuart Grehan Not Competing At Irish Open
Treaty United The Next Test For Athlone Town