18-year-old prop Sadhbh McGrath is set to make her international debut while Leinster prop Niamh O’Dowd could make hers off the bench.
Ireland will once again be captained by Kilcormac's Nichola Fryday when they face Wales in the Six Nations this weekend.
The Exeter second row will be joined in the starting line up by Tullamore RFC's Aoife Dalton who starts in the centre.
18-year-old prop Sadhbh McGrath is set to make her international debut while Leinster prop Niamh O’Dowd could make hers off the bench.
McGrath packs down alongside Neve Jones and Linda Djougang, with captain Fryday beside Sam Monaghan in the second row.
Dorothy Wall, Maeve Óg O’Leary and Brittany Hogan are selected in the back row.
There's first Six Nations appearances for fullback Méabh Deely, and Natasja Behan on the wing.
Aoife Doyle is on the other wing while Enya Breen completes the Ireland midfield.
Nicole Cronin and Molly Scuffil-McCabe are named as half-backs.
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