Australia and Fiji will be the other opponents for Andy Farrell's side.
Rugby World Cup Champions South Africa will play Ireland in Dublin for the first time in five years this November.
It will be the first of the Autumn Nations Series matches at the Aviva Stadium on Saturday November 5th.
The second test is against Fiji one week later, with Australia to provide the opposition in the final test on Saturday November 19th.
Tickets will go on sale in July following the normal distribution to rugby clubs.
Meanwhile, it's been announced that the Rugby World Cup is going to the United States.
It's been confirmed that the men's tournament in 2031 will be held in America.
The 2027 tournament has been awarded to Australia, following a meeting of the World Rugby Council in Dublin.
The 2025 Women's World Cup will be staged in England, with the 2029 renewal in Australia and the 2033 event in the USA.
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