36 are without permanent accommodation in Westmeath. 23 people are homeless in both Laois and Offaly.
8,914 people were homeless in December, a drop of 2% on the previous month.
Of those, 2,451 were children, which also represents a nearly 4% decrease on November's figures.
The Department of Housing statistics also reveal 1,077 families required homeless accommodation last month, a drop of 31 compared to November.
171 people exited from homelessness in the midlands in 2021.
36 remain homeless in Westmeath, the highest in the region.
Both Laois and Offaly have 23 adults without permanent accommodation.
The figures don't include rough sleepers, women in refuge centres and those in direct provision.