Hospitals have expanded bed capacity to cope with rising demand.
Midlands hospitals are experiencing a surge in admissions, including Mullingar, Tullamore and Portlaoise.
Additional beds have been opened to manage increased demand on capacity and resources.
Patients with non-emergency conditions are being asked to consider alternatives such as GPs, pharmacists, out-of-hours services or local injury units.
Non-urgent attendances at emergency departments are facing very long waiting times.
The HSE is stressing that all emergency cases will be seen and urges anyone with symptoms of heart attack or stroke to seek immediate help.
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