Two children died in the incident in Westmeath.
The State Pathologist has examined the scene of a fatal car fire in Westmeath.
Two children died in the blaze in Multyfarnham this evening.
Dr. Sally Ann Collis will carry out the post-mortems in the Midland Regional Hospital, Tullamore tomorrow.
Shortly before 4pm, the alarm was raised after a car with three occupants was discovered on fire on a rural road at Lackan near Multyfarnham. Gardaí and emergency services were alerted to attend at that scene.
An infant boy was removed from the scene by ambulance to Midland Regional Hospital, Mullingar where he was pronounced dead.
The remains of a girl were discovered inside the car. Her remains have been removed from the scene to Midland Regional Hospital, Tullamore.
A woman was treated at the scene for burn injuries before being air lifted to a Dublin Hospital. Her injures are understood to be serious but not thought to be life threatening.
The scene has been examined tonight by the Garda Technical Bureau and remains preserved overnight. The car has been removed from the scene and will be further forensically examined tomorrow.
Gardaí say the results of the post-mortems and the Forensic examinations will determine the course of the investigation.
An incident room has been established at Mullingar Garda Station and Senior Investigating Officer (SIO) has been appointed to lead the investigation.
A Garda family liaison officer has been appointed and An Garda Síochána will continue to support the family involved in conjunction with other state agencies.
An Garda Síochána is appealing to any person with any information in relation to this fatal incident to contact investigating Gardaí at Mullingar at 044 9384000, the Garda Confidential Line 1800 666 11 or any Garda Station.
The investigation is ongoing and further updates will follow.