Offaly came next, with Westmeath having the highest rate in the midlands.
Laois has one of the lowest infection rates of covid19 in the country.
The O'Moore county has a 7 day incident rate of 226.7 per 100,000 people, having reported 192 news cases in the past week.
Figures from the Health Protection Surveillance Centre also show, Offaly has a rate of 277.1, after 216 people tested positive for the virus in the same period.
Westmeath had the highest rate in the midlands' at 292.9, with 260 confirmed cases in the last 7 days.
Monaghan is the county worst affected nationwide, with 773.8 per 100,000 while Clare is least afflicted at 118.7.